CME Sessions at EANM’09

EANM’09 – CME Session VIII

Renal
October 12, 2009, 16:30 – 18:00
Nuclear Renography Practice and Future

Moderator: J. Buscombe (London)


Speakers:
extended
abstract
J. Frøkiær (Aarhus):
The value of renography in hydronephrosis: Physiology and Pathophysiology
P. Hawkins (London):
The Clinical Utility of Serum Amyloid P Component (SAP) Imaging in Amyloid
J. Buscombe (London):
The Utility of Nuclear Medicine in the Renal Transplant Patient


Educational objectives:

  1. Find out what is renal obstruction what does it mean at a physiological level
  2. Understand how it occurs and how can it be detected
  3. Provide an understanding of the pathogenesis and clinical features of amyloidosis
  4. Describe the basis for and the extent of qualitative and quantitative information yielded by labelled SAP studies and its use for diagnosis and monitoring amyloidosis
  5. Understand the role of nuclear medicine in assessment of a renal transplant and in managing the clinical problems faced by the transplant patient.


Summary:

The diagnosis of renovascular disease can be difficult clear cut changes in the uptake and parenchymel retention of dynamic renal tracers such as Tc-99m MAG3 are fairly diagnostic however in less extreme cases changes may be subtle. Even with the use of captopril enhancement there may still be some concern about the validity of the result. Neural networking is a method of computer aided diagnosis which enables a computer to learn patterns of abnormality form data inputs and results in determining the probability of disease One of the causes of renal failure is amyloidosis which results in deposition of the amyloid protein in a number of tissues including the kidney. The recent development of I-123 serum amyloid component P (SAP) protein has been developed as a specific tracer in amyloidosis. Both planar imaging and more recently SPECT-CT have been used to diagnose and monitor
the natural history of amyloid.
The assessment of a renal transplant by nuclear medicine has been available for 30 years despite the advent of other techniques the quantitative nature of nuclear medicine provides a unique method for assessing graft function.


Key Words:

Renovascular Hypertension, Neural Networks, Amyloid, I-123 SAP, Transpant Renography

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