EANM’06 – CME Session IV
Fusion Imaging – SPECT/CT
October 1, 2006, 16:30 – 18:00
Is there a clinical role for SPECT/CT?
Moderator: L. Mansi (Naples)
|L. Mansi (Naples):
Premises and perspectives of SPECT- CT
|O. Schillaci (Rome):
Clinical applications in Oncology
|T. Kuwert (Erlangen):
Clinical applications in non-oncological diseases
- Define the field of interest of SPECT – CT, on the basis of a cost-effective analysis evaluating both clinical data already available and possible new indications with main reference to the Emergency.
- Comprehend the rationale and the incremental diagnostic value of SPECT/CT with respect to alternative procedures, including fusion imaging based on SPECT and CT acquired separately.
- Understand the principles of CT-based attenuation correction of SPECT images and the potential impact of this methodology, becoming familiar with main technical parameters and protocols for acquiring SPECT/CT images with a hybrid device.
- Understand the usefulness of SPECT/CT in oncology and in non oncological indications as in cardiology, orthopaedics, inflammation and endocrine disorders.
- Review interesting clinical cases for selecting appropriate patients and accurately interpreting SPECT/CT studies.
SPECT – CT was proposed in 1992, with a first commercial development based on low resolution CT. First methodological approaches have been connected with the use for a CT-based attenuation correction in cardiology and, mainly in oncology and orthopaedics, in better localizing hot spots. Growing clinical applications of PET-FDG strongly supported the advent of the diagnostic CT era in hybrid systems, encouraging Industries to utilize also for SPECT-CT high resolution devices. In this session the first speaker (L.Mansi) will start defining the field of interest of SPECT – CT, on the basis of a cost-effective analysis evaluating both clinical data already available and possible new indications with main reference to the Emergency. The rationale, the economical and dosimetric justification of different systems and the incremental diagnostic value with respect to alternative procedures , including fusion imaging, will be also analysed. The second speaker (O. Schillaci) will discuss the use of SPECT/CT in oncology. The first part of the talk will describe the technical aspects, especially the basic principle of a hybrid SPECT/CT device and will provide information on how to perform a SPECT/CT study. Then the lecture will cover the different applications of SPECT/CT in oncology, using various radiopharmaceuticals and giving clinical examples, where the combination of functional and anatomical data has led to the correct diagnosis. The third speaker (T. Kuwert) will discuss the use of SPECT/CT in non-oncological diseases. This lecture will first be focussed on CT-based attenuation correction of myocardial and skeletal scintigrams and then will cover the potential impact of SPECT/CT in orthopaedic diseases, inflammation and endocrine disorders. Particular emphasis will also be given on the different techniques of registration including the various hardware – as well as software-based approaches.
SPECT-CT; fusion imaging; oncology; non oncological diseases