CME Sessions at EANM’09

EANM’09 – CME Session I

Inflammation / Infection
October 11, 2009, 08:00 – 09:30
Infection Imaging: Consolidated Points and New Approaches

Moderator: A. Signore (Rome)
Co-Moderator: E. Lazzeri (Pisa)

O. Israel (Haifa):
Labelled WBC-SPECT/CT and FDG-PET/CT in Infection – Choosing the Right Tracer and Technology
F. Jamar (Brussels):
The Added Value of CT in Hybrid Cameras for Imaging Infection
A. Signore (Rome):
New Procedures and Guidelines for Imaging Infection with WBC

Educational objectives:

  1. Identify the strength and weaknesses of two tracers – labelled WBC and FDG – and of two imaging modalities SPECT/CT and PET/CT – for assessment of infection.
  2. Develop a strategy on choosing the most appropriate tracer and imaging modality for various specific clinical indications.
  3. To appreciate the added value of CT to both SPECT & PET technology for the evaluation of infectious and inflammatory disorders, especially in orthopaedic medicine and in patients with fever of unknown origin.
  4. To have an update on recent guidelines and procedures for WBC labelling.


The aim of this CME session is to update the audience with the latest practical and methodological findings in the field of imaging infection. We have therefore stressed the comparison between WBC and FDG as well as the differences between hybrid cameras and standard imaging procedures. In particular, the first lecture will cover relevant practical aspects on the most appropriate use of labelled WBC with SPECT/CT and FDG-PET/CT for non-invasive assessment of patients with suspected or known infectious processes, addressing the current state-of-the art and recent developments in this evolving field.
The recent development of hybrid systems now provides the exquisite combination of sensitive nuclear medicine techniques and anatomical details. This combined imaging approach is of particular interest in orthopaedic medicine and in patients with undiagnosed fever, most of the latter belonging to the FUO patient category. The use of PET-CT as a firstline tool in this patient population will be discussed in details in the second lecture.
Finally, the new methodological and procedural guidelines for labelled-WBC will be discussed in the light of the availability of new “closed-systems” for labeling and of new European regulations.

Key Words:

Infection Imaging, WBC, FDG, SPECT/CT, PET/CT, Guidelines

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