CME Sessions at EANM’11

EANM’11 – CME Session XIII

CME Session XIII – Translational Molecular Imaging
October 19, 2011, 10:00 – 11:30
Preclinical Models for the Characterization and Therapy of Diseases

Moderators: S. Zitzmann-Kolbe (Berlin), L. Aloj (Naples)

P. Krimpenfort (Amsterdam):
Fast Track Production of Complex Tumour Models Starting from GEMM-Derived Embryonic Stem Cells
M. Hendriks-De Jong (Rotterdam), O. Boerman (Nijmegen):
Small Animal Imaging – PET and SPECT Advantages and Disadvantages
B. Pichler (Tübingen):
How to Monitor Therapy Effects in Animal Models?

Educational objectives:

  1. Gain insights in the design of animal models
  2. Understand the role and the potential of small animal imaging in the noninvasive biological characterization of animal disease models
  3. Develop a strategy how to use imaging techniques for preclinical therapy monitoring


This continuing education session adresses research fellows and nuclear physicians active or interested in the performance and the interpretation of preclinical nuclear cancer studies. It will cover a review of current animal models, tumor transplantation, choice of narcosis procedures, and the available imaging methodology for the characterization of disease in animals. Furthermore, the drawbacks and advantages of the different animal models and imaging modalities and the need for additional ex vivo techniques such as immunohistochemistry will be discussed. For the application of these methods in therapy monitoring the basics of data acquisition and quantification as well as their reliability will be presented. By getting an overview of the current state-of-the art and recent developments, this sessions seeks to provide a foundation to participants for refining their preclinical research practice.

Key Words:

Cancer, Disease Characterization, Therapy Monitoring, Outcome Prediction

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